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Public Health Genomics and Precision Health Knowledge Base (v9.0)
PHGKB
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
Last data update: Apr 25, 2024
. (Total: 63675 Documents since 2012)
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Utility of polygenic scores across diverse diseases in a hospital cohort for predictive modeling
TH Sun et al, Nature Comm, April 12, 2024
Future implications of polygenic risk scores for life insurance underwriting.
Tatiane Yanes et al. NPJ Genom Med 2024 9(1) 25
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Researchers optimize genetic tests for diverse populations to tackle health disparities
NIH, February 2024
Novel Polygenic Risk Score and Established Clinical Risk Factors for Risk Estimation of Aortic Stenosis.
Aeron M Small et al. JAMA Cardiol 2024
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Recent advances in polygenic scores: translation, equitability, methods and FAIR tools.
Ruidong Xiang et al. Genome Med 2024 16(1) 33
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Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
NJ Lennon et al, Nature Medicine, February 19, 2024
Polygenic Risk in Families With Spontaneous Coronary Artery Dissection.
Ingrid Tarr et al. JAMA Cardiol 2024
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Predictive improvement of adding Coronary Calcium Score and a Genetic Risk Score to a Traditional Risk Model for cardiovascular events prediction.
Margarida Temtem et al. Eur J Prev Cardiol 2024
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Validity of European-centric cardiometabolic polygenic scores in multi-ancestry populations
CC Topricneau et al, EJHG, January 5, 2024
Polygenic Risk Prediction in Diverse Populations and Contexts: Scientific and Ethical Considerations
ELSI Forum Webinar, January 12, 2025
Pragmatic Approach to Applying Polygenic Risk Scores to Diverse Populations.
Aniruddh P Patel et al. Curr Protoc 2023 3(11) e911
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Ancestry-specific polygenic risk scores are risk enhancers for clinical cardiovascular disease assessments.
George B Busby et al. Nat Commun 2023 14(1) 7105
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Power of inclusion: Enhancing polygenic prediction with admixed individuals.
Yosuke Tanigawa et al. Am J Hum Genet 2023
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Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions
S Fatumo et al, Genome Medicine, October 30, 2023
From a Fledgling Genetic Science, A Murky Market for Prediction
A Smart, Undark, October 27, 2023
Predictive capacity of a genetic risk score for coronary artery disease in assessing recurrences and cardiovascular mortality among patients with myocardial infarction.
Luis Miguel Rincón et al. Front Cardiovasc Med 2023 101254066
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Are we nearly there yet? Starts and stops on the road to use of polygenic scores.
Sowmiya Moorthie et al. J Community Genet 2023
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A linear weighted combination of polygenic scores for a broad range of traits improves prediction of coronary heart disease.
Kristjan Norland et al. Eur J Hum Genet 2023
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Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores.
Adrian I Campos et al. Nat Genet 2023
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Principles and methods for transferring polygenic risk scores across global populations
L Kachuri et al, Nature Rev Genetics, August 24, 2023
Application of genetic risk score for in-stent restenosis of second- and third-generation drug-eluting stents in geriatric patients.
Yu-Ling Hsu et al. BMC Geriatr 2023 23(1) 443
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No association between genetic markers and hypertension control in multiple cross-sectional studies.
Valeriya Chekanova et al. Sci Rep 2023 13(1) 11811
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Genotype error due to low-coverage sequencing induces uncertainty in polygenic scoring
E Petter et al, AJHG, July 24, 2023
Improving polygenic score prediction for coronary artery disease across populations of diverse ancestry
Nature Medicine, July 10, 2023
Contemporary Polygenic Scores of Low-Density Lipoprotein Cholesterol and Coronary Artery Disease Predict Coronary Atherosclerosis in Adolescents and Young Adults.
Rodrigo Guarischi-Sousa et al. Circ Genom Precis Med 2023 e004047
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A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.
Aniruddh P Patel et al. Nat Med 2023
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Impact of comorbidity on family genetic risk profiles for psychiatric and substance use disorders: a descriptive analysis.
Kenneth S Kendler et al. Psychol Med 2023 53(6) 2389-2398
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Leveraging trans-ethnic genetic risk scores to improve association power for complex traits in underrepresented populations.
Haojie Lu et al. Brief Bioinform 2023
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The role of polygenic risk scores in breast cancer risk perception and decision-making.
Leslie Riddle et al. J Community Genet 2023
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Accelerometer-measured intensity-specific physical activity, genetic risk and incident type 2 diabetes: a prospective cohort study.
Mengyun Luo et al. Br J Sports Med 2023
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Page last reviewed:
Feb 1, 2024
Page last updated:
Apr 25, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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